This issue of CTBTO Spectrum looks at the many interactions between the NAWE region and the CTBT, at the anniversary activities marking the adoption of the Treaty ten years ago, as well as at the achievements of the CTBTO Preparatory Commission and future challenges. Several hundred participants listened to presentations of world-renowned scientists in the first scientific symposium organized by the PTS, which was held from 31 August to 1 September 2006 at the Hofburg in Vienna. Delegations and scientists engaged in a multi-disciplinary exchange of ideas and explored synergies between the global scientific community and the CTBTO Preparatory Commission.